Streptomycin Sulfate (Streptomycin) is a common antibiotic used usually against tuberculosis. Streptomycin inhibits CHON synthesis of gram (-) bacteria.

Generic Name

streptomycin sulfate

Drug Class

Antibiotic, anti-tubercular,anti-infective

Specific Action

• Inhibits CHON synthesis strains of gram negative bacteria, mechanisms of lethal action and fully understood, but functional integrity of cell membrane appears to be disrupted.

Indication

• Infections caused by susceptible strain of mycobacterium tuberculosis.
• Serious infections caused by susceptible strains of Yersinia Pestis

Contraindication

• Allergy to aminoglycosides, pregnancy, lactation, Herpes vacinia fungal infection.

Stock Dose

• 1 gram* / vial
• *Each vial contains Streptomycin Sulfate USP equivalent to 1 gram Streptomycin.

Nursing Responsibilities

Nursing responsibilities when administering streptomycin

• Use in route only: give by deep IM injection.
• Ensure adequate hydration of patient before and during the therapy.
• Monitor for hearing changes.
• This drug can only be given by injection.
• Report hearing changes, dizziness, pain at injection site, rash.